Pharmaceutical giant AstraZeneca has for the first time admitted that its COVID-19 vaccine could cause a rare side effect that can lead to blood clots and death, according to court documents.
The company is fighting a class action lawsuit alleging that its inoculation, which was developed in collaboration with the University of Oxford, can result in death and serious injury.
The legal battle was initiated by Jamie Scott, a father of two, who suffered a blood clot that left him with brain damage after he was vaccinated in April 2021 amid the COVID-19 pandemic. He is seeking compensation over claims that the AstraZeneca vaccine is “defective” and less safe than was expected, an allegation the company denies.
In May 2023, AstraZeneca also insisted that “we do not accept that TTS [Thrombosis with Thrombocytopenia Syndrome] is caused by the vaccine at a generic level,” as quoted by The Daily Telegraph.
TTS is a rare condition, in which a person develops blood clots which can reduce blood flow when combined with a low platelet count, prompting difficulties with stopping bleeding. TTS symptoms include severe headaches and abdominal pain.
Despite previous denials, AstraZeneca said in documents which were submitted to the UK High Court in February, that “it is admitted that the AZ vaccine can, in very rare cases, cause TTS. The causal mechanism is not known.”
“Further, TTS can also occur in the absence of the AZ vaccine (or any vaccine),” the company added, as quoted by the Telegraph.
AstraZeneca insists the available data shows the drug has “an acceptable safety profile,” and that “regulators around the world consistently state that the benefits of vaccination outweigh the risks of extremely rare potential side effects.”
Dozens of Western countries suspended the use of AstraZeneca’s vaccine in the spring of 2021 over fears it may have caused some patients to develop blood clots. At the time, the head of the European Medicines Agency’s (EMA) vaccines strategy, Marco Cavaleri, said that there was an evident link between AZ vaccine intake and blood clots in the brain, but maintained that the benefits still outweighed the risks.
According to World Health Organization data, the AstraZeneca coronavirus vaccine has an efficacy of 72%. As of April 2021, over 17 million people had received the jab in the EU and the UK, with just under 40 cases of thrombosis reported, according to the company.
